Gomez, who traveled to Comic-Con from Mexico City, said the pairing of both heroes left her optimistic about a new Superman film.
Benjamin Ha, who dressed as Superman to his wife's Wonder Woman, said bringing the two superheroes together will yield fireworks.
"They're both alpha males," he said.
Saturday's announcement about the film follows DC Entertainment's debut last month of the Greg Pak-written Batman/Superman comic, an ongoing monthly series illustrated by Jae Lee that was the top-selling title among comic books in June.
The book pairs the two characters together a time in their lives when they're both young and still adapting to being superheroes.
Superman and Batman have also been at odds in comic books, too. In Frank Miller's dark telling of The Dark Knight Returns, a four-issue mini-series from the 1980s, Batman came out of retirement while Superman became a tool of the federal government.
Production on the Superman sequel is set to begin next year. The film is expected to be released in the summer of 2015.