Part of the neighborhood southwest of the airport was evacuated. Buses transported up to 200 people to a nearby shelter, Red Cross volunteer Jackie Lincoln said.
Mike Daigle, executive director of the St. Joseph County Airport Authority, said the jet attempted a landing, went back up and maneuvered south to try another landing, but eight minutes later the airport learned the plane was no longer airborne.
"There was an indication of a mechanical problem," Herwig said.
Stan Klaybor, who lives across the street from the crash scene, said the jet clipped the top of one house, heavily damaged a second, and finally came to rest against a third. Neighbors did not know if a woman living in the most heavily damaged house was home at the time, and a young boy in the third house did not appear to be seriously injured, Klaybor said.
"Her little boy was in the kitchen and he got nicked here," Klaybor said, pointing to his forehead.
His wife, Mary Jane, regularly watches planes approach the airport.
"I was looking out my picture window. The plane's coming, and I go, 'Wait a minute,' and then, boom," she said.
"This one was coming straight at my house. I went, 'Huh?' and then there was a big crash, and all the insulation went flying," she said.