The Huntington VA treated more patients during the period and doled out almost twice as many prescriptions as the Beckley center, the report says.
The Huntington VA saw 340,167 patients and issued almost 494,500 prescriptions. There were 24,610 patients in 2001 compared with 16,779 prescriptions. There were about 4,000 more patients and a total of 44,558 prescriptions in 2012.
The number of patients peaked in 2006 at 29,543, with prescriptions reaching their highest total - 56,332 - in 2008.
Again, hydrocodone was prescribed the most. In 2001, there were 7,166 prescriptions compared with 24,610 patients. With about 28,500 patients in 2012, there were 32,141 hydrocodone prescriptions.
The report doesn't specify if there is any overlap in patients treated at either hospital from year to year, but it is likely given population totals for the area.
Prescriptions for the four medications nationally have increased by 270 percent since 2001, compared with a 41 percent increase in VA patients during the same time span, according to the report.
Hydrocodone-acetaminophen was the third-most prescribed medication through Medicare in the country in 2010, according to a report from ProPublica, another nonprofit investigative journalism platform.
The report found the medication was the top prescribed drug in 2010 for all West Virginians participating in Medicare Part D, the program's prescription drug plan.
A spokeswoman for the Beckley VA said she could not immediately comment but said she might be able to provide some information in the near future. A spokeswoman for the Huntington VA referred comment to the national VA. No one answered a call placed Monday afternoon to the national office of VA media relations.
A spokeswoman for the state Department of Veterans Assistance did not immediately respond to messages.
National VA representatives sent a statement to the Center for Investigative Reporting saying the VA is working to address any issues with prescription drug abuse by veterans.