Al-Moallem said some regional and international players are seeking to escalate the conflict and create "a state of instability to ensure the need for foreign interference." He insisted that several countries are using the U.N. to meddle in internal Syrian affairs by calling on Assad to step down.
"This is a blatant interference in the domestic affairs of Syria, and the unity of its people and its sovereignty," he said.
Al-Moallem urged the General Assembly's 192 other members to exert pressure to end the violence.
"I say to those countries: enough illusions. And I invite the national opposition to work together to stop the shedding of Syrian blood, and to sit at the dialogue table and participate in the making of the present and future Syria," al-Moallem said.
In a jab clearly aimed at the U.S., Britain and France and their support for the revolution in Libya that ousted Moammar Gadhafi, al-Moallem said that "permanent members of the Security Council, who launched wars under the pretext of combating terrorism now support terrorism in my country."
Extremists have been encouraged to enter Syria to carry out terrorist acts in the name of "jihad" in collaboration with Syrian terrorists, Al-Moallem said, citing international and Arab observers.
"Syria has lost thousands of martyrs from the military and civilians as a price of its quest to defend the integrity of the Syrian state and its citizens in the face of this global terrorist campaign," he said.
Al-Moallem met with Secretary-General Ban Ki-Moon before his speech Monday. Ban, according to a statement by his press office, "raised in the strongest terms the continued killings, massive destruction, human rights abuses, and aerial and artillery attacks committed by the government. He stressed that it was the Syrian people who were being killed every day, and appealed to the Government of Syria to show compassion to its own people."