"In times of increased global unrest and economic insecurity, it's essential that we come together - as Democrats and Republicans, business and labor, Wall Street and Main Street - to put our country first and solve our problems instead of passing them on to the next generation," Manchin said in a press release announcing the ad.
The ad will be featured on local televisions stations and can be seen online at Manchin's campaign website.
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Manchin and Raese will have their first debate of the campaign season in early October.
The Eastern Panhandle's Shepherd University will host the debate Oct. 2 in Reynolds Hall on the Shepherdstown campus.
The master of business administration program is arranging the debate. West Virginia Public Radio's Cecelia Mason will serve as the moderator. Area journalists will pose questions on such topics as health, energy, jobs, education and the environment.
The Shepherd University Foundation is handling inquiries about tickets for the debate at 304-876-5397.
Manchin, Raese and Mountain Party candidate Bob Henry Baber also are expected to debate Oct. 10 at West Virginia Northern Community College in Wheeling.
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West Virginia Democrats are holding their main annual fundraiser just in time for the general election.
The party is rescheduling its Jefferson-Jackson Dinner for Oct. 27 at the Charleston Civic Center.
Democrats postponed the event in August as West Virginians recovered from storms that cause widespread power outages.
Former congressional leader and presidential candidate Dick Gephardt remains the dinner's keynote speaker. The Missouri Democrat served as House majority leader from 1989 until 1995, and then as minority leader until 2003.
The annual JJ Dinner is a key fundraiser for the state Democratic Party. Tickets are $75 per person or $1,000 for a table of 10.
Compiled from staff, wire reports