WVU went inside, but 7-foot center Jeff Withey blocked back-to-back shots and Kansas grabbed the rebound and dribbled away the rest of the clock.
"What more could we have done?" Coach Bob Huggins said. "We could have ran what we were supposed to run in the fashion it was supposed to be run."
Murray led all scorers with 17 points and added eight rebounds. Staten had 14 points, but just one assist in 32 minutes. The Mountaineers shot 37 percent against the NCAA's leader in field-goal percentage defense and got nothing from their top perimeter threats.
Freshmen Eron Harris and Terry Henderson combined to miss all seven of their shots and were 0-for-5 from 3-point range. Henderson was scoreless and Harris, who was in double figures the past four games and had averaged 15.8 points, made just two free throws.
The Jayhawks won the rebounding battle for the 17th time (36-27) and gave WVU only nine offensive rebounds and seven second-chance points.
"The big key with West Virginia is that if they shoot a marginal percentage, you have to keep them off the glass because they're a great offensive rebounding team," Kansas Coach Bill Self said. "We actually did a good job with defensive rebounding."
Kansas improved to 19-0 when allowing the opponent to shoot below 50 percent and 14-0 when allowing fewer than 60 points.
Withey had 15 points, seven rebounds and four blocked shots. Releford made 7 of 9 shots for 15 points and McLemore, second in the Big 12 in scoring and leading in field-goal, free-throw and 3-point percentage, had 13 points. The Jayhawks shot 54.1 percent, but let WVU stick around by missing 16 free throws in 34 attempts.
"The thing I don't like is when you're playing with a lead late, you tend to get passive or have guys try to make a great play instead of a good play, and that happened (Monday)," Self said.
The Mountaineers quickly found themselves precisely where they did not want to be. WVU stole the ball away from Kansas on the game's first possession and Deniz Kilicli made two free throws, but the Jayhawks made back-to-back 3-pointers and their first three shots as part of 16 unanswered points in a 22-5 run.
WVU was again down by double digits in a Big 12 game, but this time after just 5:11. The Mountaineers missed their first seven shots and had three turnovers before Kilicli's basket at the 12:36 mark. That made it 16-4. The Mountaineers would need a timeout down 29-14, when they were just 3-for-14 from the floor to 11-for-20 for Kansas.
Contact sportswriter Mike Casazza at mi...@dailymail.com or 304-319-1142. His blog is at bogs.dailymail.com/wvu.