The game played out very much like the first meeting between the squads won by Huntington 69-50 at George Washington.
The Highlanders (18-4) also led that game by just one at halftime.
Kelly Jo Harrison led the Patriots with 20 points and nine rebounds with Rachel Ward adding 16 and Alanna Mobayed 10.
SPRING VALLEY 82, PARKERSBURG 51 - When Parkersburg (13-9) cut Spring Valley's early lead to just four points at 24-20 Timberwolves' coach Bo Miller called a quick timeout.
"I had to re-explain to them how we run our press-breaker," Miller said. "They were forcing us into too many mistakes."
That little refresher was all his players needed.
Spring Valley proceeded to take off on a 13-2 run and the Big Reds never recovered.
"Our transition defense killed us," Parkersburg coach Kenny DeMoss said. "We weren't getting back."
The Timberwolves hit 54 percent from the floor in each half as their quick ball movement led to one open shot after another. A total of eight different players finished with assists and 12 scored.
Madison Morris paced Spring Valley with 16 points while Kenny Walker and Imani Ward each finished with 11 points to lead Parkersburg.