Browne responded with a jumper with 1:46 left to play, but it was the last basket for the Mountaineers. They missed their last two shots in regulation and then went 0-for-11 in overtime.
UConn took the lead for good when Lamb rolled off a screen and made a 3 against close defense by Bryant.
"I'm 6-1, he's about 6-5, maybe 6-6 - I contested it, but he's tall and he's going to get that shot off whether I want him to or not," Bryant said.
Jones missed a jumper on the next possession, but UConn's Ryan Boatright missed two free throws with 34 seconds left. Bryant drove into the lane and into a defender and turned the ball over again. Boatright was fouled and made a free throw.
Paul Herbert Williamson, WVU's situational 3-point specialist, entered the game and was wide open on the right side, where he likes to shoot. He instead pump-faked and drove and unsuccessfully tried to draw a foul.
The Mountaineers called a timeout, missed three more 3s on the game's final possession and then got a look at the stat sheet. They saw a 47-31 rebounding advantage and scoring edges in points in the paint (32-30), point off turnovers (15-10) and second-chance points (25-8).
"We beat them in basically every statistical category, except the scoreboard, and that's what it really comes down to," Jones said.
"At the end of the game we let them drive and they got easier shots than we did. And at the end, they played great defense on us."
The senior All-Big East pick from nearby Mount Vernon led WVU with his 21st double-double and had 25 points and 10 rebounds. Bryant shot 4-for-14, but had 20 points. Forward Dominique Rutledge had six points, 11 rebounds and three assists off the WVU bench.
Napier had 26 points, four rebounds, six assists, three blocks and three steals and bothered Bryant's offense throughout
"I thought Shabazz was close to magnificent," Huskies Coach Jim Calhoun said.
Lamb had 22 points and eight rebounds and Boatright added 10 points, three assists and two steals.
The Huskies blocked 10 shots and made 51.9 percent of their shots after halftime. It's the fourth time they've won a game this season after trailing by 10 points or more - and the second time against WVU.
The Mountaineers wasted a 10-point lead with a similar collapse on the road against the Huskies in January.
"I truly believe that a coach couldn't be prouder - and I honestly mean this," Calhoun said. "It's a funny word to throw around because you know you've had some great moments to be proud ... but that's one heck of a win.
"It's two teams finding different ways there - frontcourt power and backcourt quickness. So it was a great battle, even if they had won the game. And they could have won the game, but my guys weren't going to let them. Again, I'm so proud."
Contact sportswriter Mike Casazza at mi...@dailymail.com or 304-319-1142.