The trash talking already has begun.
"I'm going after wine as a one-trick pony," Ireland said.
Ireland, 50, of Charleston, said beer is a much more complex beverage that is harder to perfect and thus should complement the cuisine better than wine.
"Wine could basically make itself if you don't interfere with it," he said with a laugh. "If apes were clever enough to write on cave walls, they would tell you they were already drinking wine way back then."
Brown, 66, of Charleston, said he would let the wine do the talking for him.
"He (Ireland) does a good job expounding," Brown said with a chuckle. "But he has to do the best he can with an inferior beverage."
He said wine is a "grown-up" drink while beer is for a younger crowd that tends to drink to excess.
"And he talks about apes drinking wine," Brown said. "Well, if apes were drinking wine, imagine how much better it has gotten since then."
Brown and Ireland, who are friends, say they enjoy friendly competition and lighthearted debate about the pros and cons of beer versus wine.
Both are interested in educating the public about their favorite beverages.
Ireland pointed out that beer has had an image problem in the United States over the past 100 years - especially since Prohibition.
"Beer became associated as a workingman's drink and it got sidelined with pub food," Ireland said.
"Beer and brewing are fine arts," he added. "But it's an art form you can drink."
Brown also wants to overcome some common misconceptions about his beverage of choice. Cost is one.
Brown often spends less than $20 a bottle.
"I pride myself on finding good wines that are $8 to $15 a bottle," he said.
Brown also plans to address a common misconception Saturday when he pairs a red wine with a fish course. He picked a medium-bodied red to go with the Calabrian shrimp.
"I thought the red wine would go well with the spicy nature of the shrimp with tomato," Brown said. "It should be a good match.
"This is going to be a lot of fun and it's for a good cause."